Shiseido Eudermine Revitalizing Essence 4.2oz/125 ml. A softener for smooth, supple skin. Prized in Japan for over a century, Shiseido Eudermine is one of Shiseido's oldest products introduced in 1897. This softening lotion delivers immediate moisture and responds to changes in the climate to keep skin's moisture level constant regardless of location or time of year. Subtly perfumed with an accent of rain-washed peonies that seems to relax your entire being. Skin radiates, its softness evoking that of a flower petal. All Skin Types. Dermatologist-Test12ed.